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CE Hours: 1.5

Seq #: 73 - Microbes and Oral Cancer

William Coley, a surgeon who practised in New York in the late 19th Century had an interesting theory about what causes cancer: he thought cancer was caused by a microbe. Today, we now know that about 15%-20% of cancers have a microbial cause, including Burkitt's lymphoma (Epstein-Barr virus), cervical, anal and oropharyngeal cancers (high-risk types of human papillomavirus), gastric cancer (Helicobacter pylori) and liver cancer (hepatitis B and C viruses). There is new evidence on the role of Fusobacterium nucleatum in the early stages of colorectal cancer development. In this symposium, we propose to discuss the recent advances on the association of microbes on oral cancer based on experimental evidence and discuss the strength of this new evidence to raise further clinical research in this field.

Learning Objectives:

  • Highlight the role played by microbes in other cancers of the body and examine the controversies related to microbes and oral cancer.
  • Update the knowledge through a systematic review on the association of candida with oral leukoplakia and its role in malignant transformation.
  • Reflect on specific microbes and the bacteriome so far known to be associated with oral cancer. What new research is needed. HPV oncogenesis in oral cancer

Supported by: Henry Schein Cares - Annual Grant to IADR for Oral cancer education (Greenspan and Warnakulasuriya)

Financial Interest Disclosure: NONE

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